Have been completely working off of VMWare ThinApp 4.6.1 virtualized Office 2010 application for a few days now and for the most part have had a lot of success.  The activation issues and some of the known problems were resolved with the ThinApp 4.6.1 release.   See shameless copy post here for general instructions...

<a href="http://blogs.egroup.jasonmangone.com/?p=3688">http://blogs.egroup.jasonmangone.com/?p=3688</a>

However, I have ran into some issues surrounding Outlook 2010, MSIEXEC, etc... that have caused issues launching the virtualized Outlook.  Most of these issues seem to be related to License Version, Packager OS and Desktop OS.  Remebering a few old but still relevant Office pointers allowed me to make it 100% reliable (and fast!).

Packager:  WinXP SP3 32bit

Desktop: Win7 64bit Ultimate

ThinApp version: 4.6.1

Office Version: Professional retail key

Instructions can vary if there are changes to the rules above but if you follow the instructions in the link above you will most likely be able to set up a mail account but after that you will get the "Could Not Start Outlook error" after a MSI installer crashes with another error.  You will see issues like...
<div><span style="font-size: xx-small">Product: Microsoft Office Professional Plus 2010 -- Error 1719. The Windows Installer Service could not be accessed. This can occur if the Windows Installer is not correctly installed. Contact your support personnel for assistance.</span></div>
and...
<div><span style="font-size: xx-small" lang="EN">Failed to connect to server. Error: 0x800401FE</span></div><br /><br />

To resolve these take a look at the "Issues with ThinApp and Microsoft Office 2010" kb article on VMWare's site.  Pick out the changes that match your environment.  In my case it was these changes to the HKEY_LOCAL_MACHINE file.

<a href="http://kb.vmware.com/selfservice/microsites/search.do?language=en_US&amp;cmd=displayKC&amp;externalId=1022287">http://kb.vmware.com/selfservice/microsites/search.do?language=en_US&amp;cmd=displayKC&amp;externalId=1022287</a>
	<li>
<div>The Outlook component of Office 2010 fails to launch after account configuration when deployed to 32-bit Windows 7 unless these entries are added to the bottom of HKEY_LOCAL_MACHINE.txt in the project directory:</div>
isolation_full HKEY_LOCAL_MACHINESoftwareMicrosoftWindowsCurrentVersionInstallerUserDataS-1-5-18ComponentsCC427126E291CBE47960B02470798141
Value=00004102110000000000000000F01FEC
REG_SZ~02:SOFTWAREMicrosoftWindows SearchProtocolHandlersMapiProgID#2300

isolation_full HKEY_LOCAL_MACHINESoftwareMicrosoftWindowsCurrentVersionInstallerUserDataS-1-5-18Components1C142428AC6D17249BC6F1CEA00887F3
Value=00004102110000000000000000F01FEC
REG_SZ~02:SOFTWAREMicrosoftWindowsCurrentVersionPreviewHandlers{435fdba0-964c-43a7-8aff-cc94e21b2249}#2300

isolation_full HKEY_LOCAL_MACHINESoftwareMicrosoftWindowsCurrentVersionPreviewHandlers
Value={435fdba0-964c-43a7-8aff-cc94e21b2249}
REG_SZ~Microsoft Office Outlook MAPI Preview Handler#2300

isolation_full HKEY_LOCAL_MACHINESOFTWAREMicrosoftWindows SearchProtocolHandlersMapi

isolation_full HKEY_LOCAL_MACHINESOFTWAREMicrosoftWindows SearchProtocolHandlersMapi
Value=ProgID
REG_SZ~Outlook.Search.MAPIHandler.1#2300

Happy ThinApping!</li>
 
