The Blob enhancements that are available with SQL 2008/SharePoint 2010 are a very welcomed enhancement for organizations with large amounts of files. It allows your files to be stored on disk, rather than in your database. This is great for many reasons...
<ul>
	<li>Smaller database size</li>
	<li>Faster databases (Especially with caching!)</li>
	<li>When storing the files on disk, you could utilize dedupe technology to reduce the amount of space your files take up! This is huge!</li>
</ul>
<div>There are many 3rd party tools that handle this for you on a granular level as well.  You can specify file types, sizes, etc that should be stored in the BLOB, rather than in SQL.</div>